Different Typing Characteristics of Amyotrophic Lateral Sclerosis Model Mice and Their Significance in Research Progress

Authors

  • Tianqi Wang Department of Acupuncture and Massage, School of Traditional Chinese Medicine, Capital Medical University
  • Tianyi Liang School of Traditional Chinese Medicine, Capital Medical University, Beijing, China
  • Shuai Niu Department of Vascular Surgery, Hebei Provincial People's Hospital, 348 Heping West Road, Shijiazhuang City, Hebei Province, China
  • RuQi Zhou School of Traditional Chinese Medicine, Capital Medical University, Beijing, China
  • Yiwen Zhang School of Traditional Chinese Medicine, Capital Medical University, Beijing, China

Keywords:

Amyotrophic lateral sclerosis, Different types, Model mouse

Abstract

Amyotrophic lateral sclerosis (ALS) is a motor neuron disease of unknown etiology, characterized by progressive muscle atrophy, weakness, and paralysis, ultimately leading to death due to respiratory failure. The pathogenesis of this disease remains unclear, and there are many clinical subtypes, such as SOD1, FUS, TDP-43, etc. This article will elaborate on the mechanisms and latest progress of the relevant subtypes of ALS, as well as analyze the differences among model mice.

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Published

2025-06-30

Issue

Vol. 95 No. 3 (2025): Volume 95, Issue 3

Section

Original Articles

How to Cite

Tianqi Wang, Tianyi Liang, Shuai Niu, RuQi Zhou, and Yiwen Zhang , trans. 2025. “Different Typing Characteristics of Amyotrophic Lateral Sclerosis Model Mice and Their Significance in Research Progress”. Human Biology 95 (3): 1140-48. https://www.humbiol.org/Home/article/view/430.